Related Experiment Video

Updated: May 19, 2026

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
04:19

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury

Published on: June 20, 2017

Long-term consequences of mild traumatic brain injury

Roberto J Rona

    The British Journal of Psychiatry : the Journal of Mental Science
    |September 5, 2012
    PubMed

    More Related Videos

    Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury09:49

    Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

    Published on: January 20, 2023

    Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion04:54

    Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

    Published on: April 19, 2024

    Related Concept Videos

    Traumatic Brain Injury l: Introduction01:28

    Traumatic Brain Injury l: Introduction

    DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
    Secondary Spinal Cord Injury llI: Pathophysiology01:25

    Secondary Spinal Cord Injury llI: Pathophysiology

    Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
    Traumatic Memory01:20

    Traumatic Memory

    Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual remembers mundane...
    Long-term Depression01:03

    Long-term Depression

    Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
    Calcium Ion Concentration Mechanism
    If over time, all...