Growth hormone therapy in Turner syndrome
1Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7032, USA. mld@med.unc.edu
Pediatric Endocrinology Reviews : PER
|September 6, 2012
Abstract:
Short stature is the single most common physical abnormality in Turner syndrome (TS) with adult stature averaging 20 cm shorter than that of the general population. Randomized, placebo-controlled studies to final adult height have proven that GH therapy is effective in increasing stature in TS. Recently, randomized, controlled studies have demonstrated that adjunctive therapies with low-dose estrogen or low-dose oxandrolone enhance stature further. These therapies may provide benefits beyond height augmentation.
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