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Updated: May 19, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Morbidity and mortality associated with Clostridium difficile ribotype 078: a case-case study
L Patterson1, M H Wilcox, W N Fawley
1Public Health Agency, Health Protection Division, Belfast, UK. lynsey.patterson@hscni.net
Abstract:
The morbidity and mortality associated with Clostridium difficile ribotype 078 were examined by comparison with other known outbreak strains. A healthcare interaction within eight weeks of a positive specimen significantly increased the likelihood of ribotype 078 compared with ribotype 027. Individuals with ribotype 078 also tended to come from community sources, have a hospital stay post specimen similar to ribotype 027 and a lower 30-day mortality, but these differences were not statistically significant. This study generates several hypotheses and a methodological platform to explore this unique profile.
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