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Related Experiment Videos

Supraglottic carcinoma: patterns of recurrence.

C K Lutz1, J T Johnson, R L Wagner

  • 1Department of Otolaryngology, University of Pittsburgh School of Medicine, Pennsylvania.

The Annals of Otology, Rhinology, and Laryngology
|January 1, 1990
PubMed
Summary

For supraglottic squamous cell carcinoma, neck recurrence is common, especially on the contralateral side. Bilateral neck dissection is recommended during surgery for better regional disease control.

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Area of Science:

  • Oncology
  • Head and Neck Surgery

Background:

  • Supraglottic squamous cell carcinoma (SCC) presents unique challenges for locoregional control.
  • Understanding recurrence patterns is crucial for optimizing treatment strategies.

Purpose of the Study:

  • To analyze recurrence patterns in patients with supraglottic SCC.
  • To evaluate the effectiveness of surgical and combined therapies.
  • To determine optimal surgical management for regional disease control.

Main Methods:

  • Retrospective review of 202 patients with supraglottic SCC and ≥2 years follow-up.
  • Analysis of treatment modalities: surgery alone vs. combined therapy.
  • Assessment of local-regional failure sites, focusing on neck recurrence.

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Main Results:

  • Overall local-regional failure rate was 23% (47/202).
  • The neck was the most frequent recurrence site (83%), with 35 cases on the undissected contralateral side.
  • Contralateral neck recurrence risk was similar for midline and unilateral lesions.
  • Radiation therapy showed limited efficacy in controlling contralateral neck metastasis (16% failure).

Conclusions:

  • Supraglottic laryngectomy, when indicated, does not compromise laryngeal primary control.
  • Routine bilateral neck dissection should be considered in surgical management of supraglottic SCC to improve regional control.
  • The high rate of contralateral neck recurrence underscores the need for comprehensive surgical staging and treatment.