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Updated: May 18, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Impact of changes in anti-doping regulations (WADA Guidelines) on asthma care in athletes
Mariana Couto1, Luís Horta, Luís Delgado
1Allergy, Asthma & Sports Unit, Immunoallergology Department, Centro Hospitalar São João E.P.E., Porto, Portugal. marianafercouto@gmail.com
Objective:
To investigate how changes to the World Anti-Doping Agency (WADA) guidelines on asthma medication requests have impacted the management of asthmatic athletes in Portugal.
Design:
Retrospective analysis of asthma medication requests submitted in 2008 to 2010.
Setting:
Portuguese Anti-Doping Authority database.
Participants:
Athletes requesting the use of inhaled corticosteroids and/or β2-agonists.
Independent Variables:
Demographic, therapeutic, and diagnostic test data.
Main Outcome Measures:
Yearly changes in number of asthma medication requests and diagnostic procedures.
Results:
We analyzed 326 requests: 173 abbreviated Therapeutic Use Exemptions (TUEs) in 2008 (objective tests not required), 9 Declaration of Use (DoU) and 76 TUEs in 2009, and 39 DoU and 29 TUEs in 2010. Spirometry was performed in 87% and 37% of athletes in 2009 and 2010, respectively; the corresponding figures for bronchoprovocation were 59% and 16%, almost all positive in both years.
Conclusions:
Applications for inhaler use have decreased by approximately half since objective asthma testing became mandatory. Our findings show that WADA guidelines have an impact on asthmatic athletes care: In 2009 a more rigorous screening was possible, leading to withdrawal of unnecessary medication. Constant changes, however, jeopardize this achievement and nowadays introduce safety issues stemming from the unsupervised use of inhaled β2-agonists.
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