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Association between diastolic dysfunction by color tissue Doppler imaging and vascular calcification on plain

Won Suk An1, Su Mi Lee, Tae Ho Park

  • 1Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea.

Kidney & Blood Pressure Research
|September 6, 2012
PubMed

Insights

Vascular calcification on X-rays is linked to left ventricular diastolic dysfunction in dialysis patients. Abdominal aortic calcification scores of 5 or higher are key indicators of this condition.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Diastolic dysfunction often accompanies left ventricular hypertrophy, predicting cardiovascular events.
  • Vascular calcification (VC) is linked to coronary artery disease in dialysis patients.

Purpose of the Study:

  • To investigate the relationship between left ventricular diastolic dysfunction (assessed by tissue Doppler imaging) and vascular calcification (assessed by plain radiographs) in dialysis patients.

Main Methods:

  • Fifty-six dialysis patients underwent evaluation for VC using plain radiographs and tissue Doppler imaging to measure the E/E' ratio.
  • Diastolic dysfunction was defined as an E/E' ratio greater than 15.

Main Results:

  • Patients with diastolic dysfunction had higher rates of coronary artery disease, elevated abdominal aortic calcification (AAC) scores (≥5), high left ventricular mass index, and larger left atrial volume.
  • The E/E' ratio was significantly higher in patients with significant VC, specific VC scores in the pelvis and hands (≥3), and AAC scores (≥5).
  • AAC scores of 5 or higher independently predicted diastolic dysfunction.

Conclusions:

  • Vascular calcification detected on plain radiographs correlates with the E/E' ratio.
  • Abdominal aortic calcification scores of 5 or higher serve as important indicators for left ventricular diastolic dysfunction in dialysis patients.
Abstract

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