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Updated: Apr 7, 2026

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
Published on: July 2, 2013
Silent stroke: not listened to rather than silent.
Monica Saini1, Kamran Ikram, Saima Hilal
1Department of Pharmacology, Clinical Imaging Research Centre, National University of Singapore, Building MD11 Level 5, Medical Drive, NUH, Singapore 117597.
Many elderly strokes are "silent" because symptoms are missed or ignored. This study found that a significant number of these silent strokes had recalled symptoms, highlighting the need for better awareness and stroke prevention education for families.
Area of Science:
- Neurology
- Geriatrics
- Radiology
Background:
- Silent brain infarcts (SBIs) affect 8-28% of the elderly population.
- SBIs are linked to increased risks of stroke and cognitive decline.
- SBIs are typically asymptomatic, but symptom recall issues may confound this.
Purpose of the Study:
- To report cases of incidentally detected acute and subacute strokes.
- To investigate whether these incidentally detected strokes were truly asymptomatic.
Main Methods:
- Utilized MRI from dementia research studies.
- Identified acute/subacute silent strokes using diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) defects.
- Collected clinical data from individuals with incidental DWI lesions.
Main Results:
- Six out of 649 subjects had incidental DWI lesions.
- Three subjects recalled symptoms temporally linked to lesions, which families had dismissed.
- Two subjects presented with focal neurological signs.
- Most subjects with incidental DWI lesions exhibited significant cognitive impairment.
Conclusions:
- A substantial proportion of
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