Ventricular tachycardia in coronary artery disease

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Updated: May 18, 2026

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

Begoña Benito1, Mark E Josephson

  • 1Sección de Arritmias, Servicio de Cardiología, Hospital del Mar, Barcelona, España.

Revista Espanola De Cardiologia (English Ed.)
|September 7, 2012
PubMed

Insights

Ventricular tachycardia (VT) remains a significant risk in coronary artery disease patients. This review covers diagnosis, electrophysiology, and ablation strategies for managing VT, alongside other therapies like drugs and ICDs.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Surgery

Background:

  • Ventricular arrhythmias significantly contribute to morbidity and mortality in patients with coronary artery disease (CAD).
  • Ventricular fibrillation is a leading cause of death during acute ischemia, while sustained monomorphic ventricular tachycardia (VT) often arises from scar tissue in healed myocardial infarction, particularly with reduced left ventricular ejection fraction.
  • Despite advances, VT risk in the CAD population remains a clinical challenge.

Purpose of the Study:

  • To review the current understanding and management of ventricular tachycardia in patients with coronary artery disease.
  • To outline diagnostic and therapeutic strategies for ventricular tachycardia associated with coronary artery disease.

Main Methods:

  • Review of diagnostic tools including 12-lead electrocardiogram and invasive electrophysiologic study.
  • Discussion of ventricular tachycardia ablation approaches based on inducibility, sustainability, and clinical tolerance.
  • Overview of alternative therapies such as antiarrhythmic drugs, surgical ablation, and implantable cardioverter-defibrillator (ICD) indications.

Main Results:

  • Electrocardiogram aids in diagnosis and localization of VT circuits.
  • Electrophysiologic studies are crucial for determining arrhythmia mechanisms and guiding ablation.
  • VT ablation strategies are tailored to individual patient factors.

Conclusions:

  • Ventricular tachycardia in CAD is a complex issue requiring a multi-faceted management approach.
  • Integrated strategies involving diagnostic studies, ablation, antiarrhythmic drugs, and device therapy are essential for optimal patient outcomes.

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