Related Experiment Video
Updated: May 18, 2026

High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
Published on: July 17, 2014
[A severe falciparum malaria case successfully treated by exchange transfusion as an adjunct therapy]
Yusuf Ziya Demiroğlu1, Ilknur Kozanoğlu, Tuba Turunç
1Başkent University Adana Teaching and Research Center, Department of Infectious Diseases and Clinical Microbiology, Adana, Turkey. yusufziya2002@hotmail.com
Severe Plasmodium falciparum malaria, characterized by high parasite counts, can be life-threatening. Exchange transfusion (ET) offers a critical supportive therapy, significantly improving outcomes in hyperparasitemic malaria cases unresponsive to standard antimalarial drugs.
Area of Science:
- Infectious Diseases
- Hematology
- Critical Care Medicine
Background:
- Plasmodium falciparum malaria presents a significant global health challenge, associated with high mortality rates even with optimal antimalarial treatment.
- Hyperparasitemia in severe P. falciparum malaria indicates a critical condition often requiring intensive management.
- Exchange transfusion (ET) is recognized as a supportive therapy for severe malaria with hyperparasitemia.
Related Concept Videos
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

