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Related Concept Videos

Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...

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Related Experiment Video

Updated: May 18, 2026

LAD-Ligation: A Murine Model of Myocardial Infarction
08:23

LAD-Ligation: A Murine Model of Myocardial Infarction

Published on: October 14, 2009

Lamotrigine related myocarditis: case report.

Turan Bayhan1, Murat Sahin, Işıl Yıldırım

  • 1Department of Pediatrics Hacettepe University Faculty of Medicine, Ankara, Turkey. turanbayhan@yahoo.com

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|September 7, 2012
PubMed
Summary

Drug-induced myocarditis is a rare complication. This case highlights lamotrigine as a potential cause, emphasizing the need to consider drug hypersensitivity in unexplained myocarditis.

Related Experiment Videos

Last Updated: May 18, 2026

LAD-Ligation: A Murine Model of Myocardial Infarction
08:23

LAD-Ligation: A Murine Model of Myocardial Infarction

Published on: October 14, 2009

Area of Science:

  • Cardiology
  • Pharmacology
  • Neurology

Background:

  • Myocarditis, inflammation of the heart muscle, can stem from various causes, including medication side effects.
  • Lamotrigine is an anticonvulsant medication commonly prescribed for epilepsy.

Observation:

  • A 15-year-old male presented with chest pain and elevated cardiac enzymes.
  • Initial evaluations revealed non-specific ECG changes, elevated troponin T and creatine kinase-MB, and mild cardiac dysfunction on MRI.
  • Infectious etiologies for myocarditis were ruled out.

Findings:

  • The patient was undergoing treatment with lamotrigine for epilepsy.
  • Discontinuation of lamotrigine led to normalization of cardiac enzyme levels.
  • A diagnosis of drug-related myocarditis attributed to lamotrigine was established.

Implications:

  • This case underscores the importance of considering drug-induced hypersensitivity in myocarditis cases where conventional causes are excluded.
  • Identifying and discontinuing the causative medication, such as lamotrigine, can be crucial for patient recovery.
  • Awareness of potential cardiac adverse effects of lamotrigine is important for clinicians managing patients on this medication.