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Central corneal thickness in a Korean population: the Namil Study
Young Hoon Hwang1, Hwang Ki Kim, Yong Ho Sohn
1Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Korea.
Investigative Ophthalmology & Visual Science
|September 7, 2012
Summary
Central corneal thickness (CCT) in Koreans averaged 530.9 μm. Thicker CCT was linked to higher intraocular pressure, younger age, male sex, and absence of hypertension.
Area of Science:
- Ophthalmology
- Corneal Research
- Public Health
Background:
- Central corneal thickness (CCT) is a critical ocular biometric parameter.
- Understanding CCT distribution and influencing factors is vital for diagnosing and managing eye conditions, particularly glaucoma.
- Population-specific data on CCT is essential for accurate clinical interpretation.
Purpose of the Study:
- To determine the distribution of central corneal thickness (CCT) in a Korean population.
- To investigate the associations between CCT and demographic factors (age, sex) and ocular/systemic parameters (intraocular pressure, anterior chamber depth, axial length, hypertension, diabetes).
Main Methods:
- Population-based study of 1259 Korean residents aged ≥40 years.
- Ophthalmic examination including ultrasonic pachymetry for CCT, optical biometry for anterior chamber depth (ACD) and axial length (AL), and Goldmann applanation tonometry for intraocular pressure (IOP).
- Statistical analysis including univariate and multivariate models to assess associations.
Main Results:
- The mean CCT was 530.9 (31.5) μm.
- Higher CCT was associated with higher IOP, longer AL, and younger age.
- Men exhibited thicker CCT than women. Hypertension was associated with thinner CCT.
- Multivariate analysis confirmed associations of CCT with IOP, age, sex, and hypertension.
Conclusions:
- The average CCT in the Korean population studied is 530.9 μm.
- CCT is significantly associated with intraocular pressure, age, sex, and the presence of hypertension.
- These findings contribute to understanding corneal biomechanics and risk factors for ocular diseases in this population.
