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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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Related Experiment Video

Updated: May 18, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

Chronic constipation in hypercalcemic patients with primary hyperparathyroidism.

A Ragno1, J Pepe, D Badiali

  • 1Unit of Internal Medicine, Nuovo Regina Apostolorum Hospital, Albano Laziale, Italy.

European Review for Medical and Pharmacological Sciences
|September 8, 2012
PubMed
Summary
This summary is machine-generated.

Chronic constipation (C) is less common in primary hyperparathyroidism (PHPT) patients now than in the past. Current constipation prevalence in PHPT is similar to controls, linked to disease severity, not PHPT diagnosis itself.

Related Experiment Videos

Last Updated: May 18, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

Area of Science:

  • Endocrinology
  • Gastroenterology
  • Clinical Medicine

Background:

  • Chronic constipation (C) is a common gastrointestinal symptom.
  • It is frequently associated with primary hyperparathyroidism (PHPT).
  • Hypercalcemia is a likely cause of C in PHPT patients.

Purpose of the Study:

  • To determine the prevalence of C in PHPT patients using a validated questionnaire.
  • To compare current C prevalence in PHPT patients with historical data.
  • To investigate the relationship between C and PHPT severity.

Main Methods:

  • Studied 55 PHPT outpatients (2006-2009) and 55 age/sex-matched controls.
  • Utilized Rome II criteria questionnaire to define C in current patients.
  • Compared current data with PHPT patients from the 1970s-1980s (anamnesis-defined C).

Main Results:

  • Current C prevalence in PHPT was 21.8% versus 12.7% in controls (not significant).
  • Historical C prevalence in PHPT (1970s-80s) was 32.7%, showing a decreasing trend (p < 0.05).
  • Reduced C correlated with lower serum calcium levels (p < 0.001); C presence linked to higher calcemia, ionized calcium, and PTH.

Conclusions:

  • Current C prevalence in PHPT patients is not significantly different from controls.
  • C prevalence in PHPT has decreased over time.
  • C in PHPT is associated with disease severity (higher calcium/PTH) rather than PHPT diagnosis alone.