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Updated: May 18, 2026

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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
Published on: January 20, 2022
Solving the convergence problem in the synthesis of triantennary N-glycan relevant to prostate-specific membrane
Maciej A Walczak1, Samuel J Danishefsky
1Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10065, USA.
Journal of the American Chemical Society
|September 8, 2012
Abstract:
The first total synthesis of triantennary, fully sialylated N-glycan of complex type is described. Two strategies for installation of sialylated antennae are explored, and both approaches converge on a global glycosylation step that delivers the desired tetradecasaccharide in good yields.

