Related Experiment Video
Updated: May 18, 2026

Application of an Amplitude-integrated EEG Monitor (Cerebral Function Monitor) to Neonates
Published on: September 6, 2017
Synchronized mechanical ventilation using electrical activity of the diaphragm in neonates
Howard Stein1, Kimberly Firestone, Peter C Rimensberger
1Department of Neonatology, Toledo Children's Hospital, 2142 North Cove Boulevard, Toledo, OH 43606, USA. Howardstein@bex.net
Abstract:
The electrical activity of the diaphragm (Edi) is measured by a specialized nasogastric/orogastric tube positioned in the esophagus at the level of the crural diaphragm. Neurally adjusted ventilatory assist (NAVA) uses the Edi signal as a neural trigger and intrabreath controller to synchronize mechanical ventilatory breaths with the patient's respiratory drive and to proportionally support the patient's respiratory efforts on a breath-by-breath basis. NAVA improves patient-ventilator interaction and synchrony even in the presence of large air leaks, and might therefore be an optimal option for noninvasive ventilation in neonates.
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