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Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Related Experiment Video

Updated: May 18, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

Building a clinical trial process in oncology.

Heather Benzel1, Barb Nickel

  • 1Saint Francis Medical Center, Grand Island, Nebraska 68803, USA. hbenzel@sfmc-gi.org

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society
|September 8, 2012
PubMed
Summary

Clinical trials provide cancer patients access to novel therapies and medical advancements. Oncology infusion nurses play a vital role in ensuring patient safety and advocating for care within these evolving research environments.

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Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
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Area of Science:

  • Oncology
  • Clinical Research
  • Nursing

Background:

  • Clinical trials represent a pathway for patient participation in medical advancement.
  • Oncology research is rapidly evolving, offering promising new cancer treatment options.
  • Managing clinical trials necessitates comprehensive education and interdisciplinary collaboration.

Purpose of the Study:

  • To highlight the critical role of the infusion nurse in oncology clinical trials.
  • To emphasize the unique position of infusion nurses in enhancing patient safety.
  • To underscore the importance of clinical knowledge, patient assessment, and advocacy skills for infusion nurses.

Main Methods:

  • This study focuses on the role and responsibilities of infusion nurses in clinical trial settings.
  • It examines the application of clinical knowledge and patient assessment skills.
  • Advocacy strategies employed by nurses are discussed in the context of patient protection.

Main Results:

  • Infusion nurses are integral members of the clinical trial healthcare team.
  • Nurses are uniquely positioned to identify and mitigate risks to patient safety.
  • Effective patient assessment and advocacy are crucial for navigating complex treatment protocols.

Conclusions:

  • Oncology infusion nurses are essential for the successful and safe administration of clinical trials.
  • Their expertise directly contributes to patient protection and optimal health outcomes.
  • Continuous education and strong collaborative efforts are key to high-quality cancer care in clinical trials.