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Published on: September 27, 2017
The relationship between atopic dermatitis and indoor environmental factors: a cross-sectional study among Japanese
Shigekazu Ukawa1, Atsuko Araki, Ayako Kanazawa
1Department of Public Health Science, Hokkaido University Graduate School of Medicine, Hokkaido, Sapporo, Japan.
Insights
Home environments with non-electric heating, visible mold, or odors are linked to atopic dermatitis in Japanese children. These factors, particularly mold and odors, pose higher risks for boys.
Area of Science:
- Environmental Health
- Pediatric Dermatology
- Epidemiology
Background:
- Atopic dermatitis (AD) is a common skin condition in children.
- Home environmental factors are suspected contributors to AD development.
- Understanding these links is crucial for prevention strategies.
Purpose of the Study:
- To investigate the association between home environmental factors and atopic dermatitis in Japanese elementary school children.
- To identify specific environmental risks within the home setting.
Main Methods:
- A cross-sectional study involving 4,254 children from 12 elementary schools in Sapporo, Japan.
- Atopic dermatitis diagnosis using the International Study of Asthma and Allergies in Childhood questionnaire.
- Analysis of 14 home environment factors, controlling for confounders and performing gender-stratified analysis.
Main Results:
- The prevalence of atopic dermatitis was 16.7%.
- Risk factors included non-electric heating without external ventilation, visible mold, moldy odors, and window condensation (OR 1.25-1.54).
- Visible mold and moldy odors were significant risk factors for boys (OR 1.28-1.64) but not girls.
Conclusions:
- Specific home environmental factors are associated with atopic dermatitis in Japanese children.
- Mold and poor ventilation appear to be key risk factors, especially for boys.
- Further research is recommended to validate these findings and inform public health interventions.
Objectives:
This study aimed to determine that home environmental factors were associated with atopic dermatitis in Japanese elementary school children.
Methods:
In this cross-sectional study, a total of 4,254 children in 12 public elementary schools in Sapporo city in Hokkaido, Japan were examined. Atopic dermatitis was defined using the International Study of Asthma and Allergies in Childhood questionnaire. The questionnaires also contained 14 questions about the child's home environment. To obtain multivariate-adjusted ORs for atopic dermatitis in relation to the home environment, we controlled for possible confounders including gender, school grade, parental history of allergies, number of siblings, and whether the child was firstborn. The study participants were then divided into two groups according to gender, and a stratified analysis was performed to obtain adjusted ORs for atopic dermatitis in relation to the home environment.
Results:
The prevalence of atopic dermatitis in our sample was 16.7 %. Using fully adjusted models, the risk factors for atopic dermatitis were found to be the household use of a non-electric heating system without a ventilation duct to the outside (compared to the use of an electric heating system), having visible mould in the house, having a mouldy odour in the house, and condensation on the windowpanes in the house odds ratios (OR 1.25-1.54). In our stratified analysis, having visible mould and having a mouldy odour in the house were relevantly found to be risk factors for boys (OR 1.28-1.64). However, these associations were not found among girls.
Conclusions:
To improve children's health, further study is needed to corroborate the findings.
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