Multifetal pregnancies: preterm admissions and outcomes
Tim Badgery-Parker1, Antonia W Shand, Jane B Ford
1Clinical and Population Perinatal Health Research, Kolling Institute of Medical Research, University of Sydney, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065, Australia. tbadg@doh.health.nsw.gov.au
Summary
Antenatal hospital admission is common for multifetal pregnancies, often leading to preterm birth. This study provides key data on admission rates and outcomes for twin and higher-order multiple gestations.
Area of Science:
- Maternal-Fetal Medicine
- Obstetrics
- Perinatology
Background:
- Multifetal pregnancies, including twins and higher-order multiples, present unique challenges in prenatal care.
- Understanding patterns of antenatal hospital admission is crucial for managing these high-risk pregnancies.
Purpose of the Study:
- To determine the incidence of antenatal hospital admissions in women with twin or higher-order multifetal pregnancies.
- To analyze the outcomes of these admissions, including discharge without delivery, transfer to higher care, and delivery (spontaneous or elective).
Main Methods:
- A cohort study utilizing linked birth and hospital data from 2001-2008.
- Inclusion criteria: women with twin or higher-order multiple births (≥24 weeks gestation) admitted between weeks 20-36 of pregnancy.
Main Results:
- Hospital admission occurred in 63.4% of twin pregnancies and 99.5% of triplet/quadruplet pregnancies.
- Admission reasons included preterm labor (34.2%). Outcomes varied: 46.3% discharged undelivered, 10.7% transferred, 21.1% spontaneous delivery, 21.8% elective delivery.
- A total of 10,985 admissions were recorded for 10,779 twin and 197 higher-order pregnancies.
Conclusions:
- Antenatal hospitalization is frequent for women carrying multifetal pregnancies.
- A significant proportion of these admissions result in preterm birth, highlighting the need for specialized care and resource allocation.
- This study establishes a baseline for hospital utilization in multifetal pregnancy populations.
Related Concept Videos
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Mitral Valve Prolapse III: Nursing Management
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...


