Related Experiment Video
Updated: May 18, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
Published on: July 21, 2023
Cognitive profile in persons with systolic and diastolic heart failure
Ponrathi Athilingam1, Rita F D'Aoust, Leslie Miller
1College of Nursing, University of South Florida, Tampa, FL 33612, USA. pathilin@health.usf.edu
Insights
Individuals with heart failure (HF) face higher cognitive impairment risks. This study found distinct cognitive patterns in systolic versus diastolic HF, highlighting the need for tailored interventions.
Area of Science:
- Cardiology
- Neurology
- Psychology
Background:
- Heart failure (HF) significantly increases the risk of cognitive impairment compared to the general population.
- Individuals with HF exhibit varied cognitive impairment patterns, necessitating further investigation into specific HF types.
Purpose of the Study:
- To analyze Montreal Cognitive Assessment (MoCA) scores in community-dwelling adults with systolic and diastolic heart failure.
- To identify differences in cognitive performance between systolic and diastolic heart failure groups.
Main Methods:
- Secondary analysis of a cross-sectional study involving 90 community-dwelling adults.
- Comparison of MoCA scores and specific cognitive domain performance between systolic HF (n=69) and diastolic HF (n=21) groups.
Main Results:
- A statistically significant difference in mean MoCA scores was observed between systolic (22.9 ± 2.31) and diastolic HF (24.8 ± 2.76) groups (P=.030).
- Significant differences were found in visuo-spatial/executive function (P=.026), attention (P=.049), abstraction (P=.014), and delayed recall (P=.048) between the groups.
Conclusions:
- Systolic and diastolic heart failure are associated with distinct cognitive profiles.
- Future research should focus on identifying these varying cognitive profiles to develop targeted interventions for individuals with HF.
Abstract:
Persons with heart failure (HF) have four times the risk of having cognitive impairment compared with the general population and display different patterns of cognitive impairment. This secondary analysis of a published cross-sectional study of 90 community-dwelling adults examined the Montreal Cognitive Assessment (MoCA) scores and HF differentiated as systolic and diastolic HF. Mean MoCA score was 22.9 (standard deviation±2.31) in persons with systolic HF (n=69) and 24.8 (standard deviation±2.76) in persons with diastolic HF (n=21) with statistically significant mean difference between groups (t=-2.025, P=.030). Independent t test on the eight MoCA domain scores and systolic and diastolic HF indicated significance on visuo-spatial/executive function (P=.026), attention (P=.049), abstraction (P=.014), and delayed recall (P=.048). Findings from this study support the need for including persons with systolic and diastolic HF in future researches on identifying varying cognitive profiles to plan tailored cognitive intervention.
Related Concept Videos
Pathophysiology of Heart Failure
Heart Failure IV: Classification and Diagnostic Evaluation
Heart Failure II: Pathophysiology
Heart Failure III: Clinical Manifestations
Heart Failure I: Introduction
Heart Failure VII: Nursing Interventions
