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Case fatality of patients with stroke over a 12-month period post stroke
W Mudzi1, A Stewart, E Musenge
1Department of Physiotherapy, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. witness.mudzi@wits.ac.za
Insights
High stroke mortality was observed in South Africa, with 38% of patients dying within 12 months post-discharge. Poor functional ability and short hospital stays contributed to poor stroke outcomes.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Stroke is a leading cause of death and disability globally and in South Africa.
- Limited data exists on stroke outcomes in sub-Saharan Africa.
- This study addresses the critical knowledge gap regarding stroke case fatality in the region.
Purpose of the Study:
- To determine the 12-month case fatality rate of ischaemic stroke patients after hospital discharge.
- To identify factors associated with mortality in this patient cohort.
Main Methods:
- A prospective study of 200 first-time ischaemic stroke patients at Chris Hani Baragwanath Academic Hospital.
- 12-month follow-up with assessments at 3, 6, and 12 months post-discharge.
- Functional ability assessed using the Barthel Index (BI) and Rivermead Mobility Index (RMI).
Main Results:
- The 12-month cumulative mortality rate was 38%, with 25.5% of deaths occurring within 3 months.
- Patients who died had significantly lower Barthel Index scores at discharge.
- Average hospital stay was 6 days.
Conclusions:
- Stroke carries a high mortality risk in this South African population.
- Poor functional status and potentially short hospitalizations may increase vulnerability to complications.
- Further research into post-discharge care and support is warranted.
Introduction:
Stroke is among the top 4 causes of death in South Africa and the top 10 leading causes of disability worldwide. There is a dearth of literature on stroke incidence, prevalence and outcome in sub-Saharan Africa. We aimed to establish the case fatality of stroke patients over a 12-month period post discharge from hospital.
Methods:
A total of 200 patients with first-time ischaemic stroke were recruited from Chris Hani Baragwanath Academic Hospital and followed up for 12 months. The Barthel Index (BI) and Rivermead Mobility Index (RMI) were used to establish patient functional ability and, by inference, stroke severity. Follow-up assessments were performed at 3, 6 and 12 months post discharge. Data analysis was largely descriptive in nature.
Results:
Thirty-eight per cent of patients died within the 12 month follow-up period; 25.5% within 3 months of discharge. The average length of hospital stay was 6 days. Low BI scores at discharge were observed in the majority of patients who died.
Conclusion:
The 12-month cumulative mortality was high (highest at the 3-month follow-up). The short hospital stay and poor functional ability of the patients post stroke possibly left them vulnerable to bed-rest complications, such as chest infections and pressure sores.
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