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Updated: May 18, 2026

Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
Published on: April 3, 2026
Axillary lymphadenectomy for breast cancer. A randomized controlled trial comparing a bipolar vessel sealing system
Luca Nespoli1, Laura Antolini, Claudia Stucchi
1Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy. luca.nespoli@unimib.it
Aim:
To compare safety and efficacy of a bipolar vessel sealing system (BVSS) to the conventional technique in axillary node dissection.
Methods:
116 women with breast cancer were randomized to conventional node dissection surgical technique (control; n = 58) by scalpel and monopolar cautery or using an electrothermal BVSS (study group; n = 58).
Results:
The median (range) total volume of fluid collected by drain and aspirations was 305 (30-1420) mL in the study group and 335 (80-1070) mL in the control group (p = 0.325). The median (range) total volume of lymph collected by percutaneous aspirations was 207.5 (40-1050) mL in the study group and 505 (270-705) mL in the control group (p = 0.010). The incidence of seroma was similar in both groups (p = 0.845). The axillary drain was removed earlier in the study group than in controls (p = 0.046).
Conclusion:
The use of a BVSS offers marginal advantages when compared to the conventional technique.
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