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Pregnancy associated pancreatitis revisited
Osamuyimen Igbinosa1, Sameer Poddar, Capercomorin Pitchumoni
1Department of Medicine, Saint Peter's University Hospital, 254, Easton avenue, New Brunswick, NJ 08901, USA. uyi80@yahoo.com
Clinics and Research in Hepatology and Gastroenterology
|September 11, 2012
Summary
Pregnancy-associated pancreatitis (PAP) is rare, affecting 0.001% of deliveries. It is more common in Hispanic women and those with a higher body mass index (BMI).
Area of Science:
- Obstetrics and Gynecology
- Gastroenterology
- Epidemiology
Background:
- Pregnancy-associated pancreatitis (PAP) is a rare but serious condition.
- Understanding its demographics and risk factors is crucial for improved maternal and fetal outcomes.
Purpose of the Study:
- To investigate the demographic characteristics, risk factors, and outcomes associated with pregnancy-associated pancreatitis (PAP).
Main Methods:
- A retrospective chart review was conducted for cases of acute pancreatitis (ICD-9 Code 577.0) between January 2005 and December 2009.
- Included were women aged 18-45 years who were pregnant or within 6 months postpartum.
- Controls were matched based on age, with no history of pancreatitis.
Main Results:
- The prevalence of PAP was 0.001% (29 cases per 25,600 deliveries).
- Hispanic women constituted 48% of PAP cases, showing a higher prevalence (P<0.05).
- A pre-pregnancy body mass index (BMI) over 30 kg/m² significantly increased PAP risk (65% of cases), with increasing trends observed with gestational age and parity.
Conclusions:
- Gallstone disease is the primary cause of PAP.
- PAP disproportionately affects Hispanic women, particularly in New Jersey.
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