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Published on: October 28, 2015
Optical properties of hematoporphyrin monomethyl ether (HMME), a PDT photosensitizer
Tim C Lei1, Gregory F Glazner, Michael Duffy
1Department of Electrical Engineering, Colorado Advanced Photonics Technology (CAPT) Laboratory, University of Colorado Denver, CO, USA.
Abstract:
We report on some of the optical properties of Hemoporfin (hematoporphyrin monomethyl ether, HMME), a photodynamic therapy (PDT) photosensitizer that has been in clinical trials in China since the early 1990s. We characterized the photosensitizer on the basis of one- and two-photon absorption and fluorescence emission. The effects of photobleaching were probed to characterize its decay kinetics. Additionally, we determined time resolved fluorescence and thermal effects on fluorescence and absorption properties.
