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Updated: May 18, 2026

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
Published on: August 23, 2024
Phenolic antioxidants isolated from the flowers of Osmanthus fragrans
Chien-Ya Hung Hung1, Yu-Cheng Tsai, Kuo-Yu Li
1Department of Food Nutrition, Chung Hwa University of Medical Technology, No.89, Wenhua 1st St., Rende Dist., Tainan City 71703, Taiwan. chienya187@yahoo.com.tw
Abstract:
O. fragrans has slightly less antioxidative activity than green tea. Five phenolic compounds, tyrosyl acetate (1), (+)-phillygenin (2), (8E)-ligustroside (3), rutin (4), and verbascoside (5), were isolated from the CHCl3 sub-extract of O. fragrans. The structures were elucidated by interpreting their spectral data. Evaluation of the antioxidative property of the isolated (+)-phillygenin (2), rutin (4), and verbascoside (5) revealed strong DPPH radical scavenging activity, with IC50 values of 19.1, 10.3, and 6.2 μM, respectively. These isolates also exhibited an H2O2 scavenging ability, with IC50 values of 10.5, 23.4, and 13.4 μM, respectively.
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