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Infant botulism following honey ingestion
C O Abdulla1, A Ayubi, F Zulfiquer
1Paediatrics Department, BHR University Hospitals, London, UK. cheriya.abdulla@bhrhospitals.nhs.uk
BMJ Case Reports
|September 11, 2012
Summary
A 3-month-old infant developed severe floppiness due to infant botulism, caused by honey ingestion. Prompt treatment with specific antibodies led to a full recovery and normal development.
Area of Science:
- Pediatrics
- Neurology
- Toxicology
Background:
- Infant botulism is a rare but serious condition affecting infants.
- It is caused by the toxin produced by Clostridium botulinum bacteria.
- Honey is a known source of Clostridium botulinum spores.
Observation:
- A 3-month-old, otherwise healthy infant presented with sudden onset of generalized floppiness.
- Clinical examination revealed lower motor neuron type muscle weakness.
- Initial investigations were crucial for diagnosis.
Findings:
- The infant's condition was diagnosed as a neuromuscular junction disorder secondary to botulism toxicity.
- Further testing confirmed the botulism toxicity was linked to honey ingestion.
- The causative agent was identified as Clostridium botulinum toxin.
Implications:
- Early diagnosis and prompt treatment with specific antitoxin are critical for recovery.
- This case highlights the importance of avoiding honey in infants under one year old.
- Successful treatment resulted in complete recovery and normal growth and development.