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Related Experiment Videos

Speech therapy in primary progressive aphasia: a pilot study.

Luísa Farrajota1, Carolina Maruta, João Maroco

  • 1Memory Clinic, Faculty of Medicine of Lisbon and Hospital de Santa Maria, Lisbon, Portugal.

Dementia and Geriatric Cognitive Disorders Extra
|September 11, 2012
PubMed
Summary

Speech and language therapy (SLT) may improve naming abilities in primary progressive aphasia (PPA). This study suggests SLT offers benefits for PPA patients, warranting further investigation in controlled trials.

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Area of Science:

  • Neuroscience
  • Neurology
  • Speech and Language Pathology

Background:

  • Primary progressive aphasia (PPA) is a neurodegenerative condition lacking effective pharmaceutical treatments.
  • Cognition-based interventions are potential alternatives, but their efficacy requires further exploration.
  • The study investigates the impact of speech and language therapy (SLT) on naming deficits in PPA.

Purpose of the Study:

  • To evaluate the effect of speech and language therapy (SLT) on the naming abilities of individuals with primary progressive aphasia (PPA).

Main Methods:

  • An open, parallel, prospective longitudinal study was conducted across two centers.
  • Twenty PPA patients were enrolled, with 10 receiving 1 hour/week of SLT for 11 months and 10 serving as a historical control group.
Keywords:
Cognitive rehabilitationDementiaPrimary progressive aphasiaSpeech and language therapy

Related Experiment Videos

  • The primary outcome was measured by changes in naming performance using the Snodgrass and Vanderwart naming test.

    • Main Results:

    • No significant demographic or clinical differences were observed between the intervention and control groups at baseline.
    • A mixed repeated measures ANOVA indicated a significant positive effect of SLT on naming test performance (F(1,18) = 10.763; p = 0.005).

    Conclusions:

    • The findings suggest that speech and language therapy (SLT) may offer benefits for individuals with primary progressive aphasia (PPA).
    • Limitations include the non-randomized, open-label design with a historical control group.
    • Further research, including randomized, controlled, rater-blind clinical trials, is recommended to confirm these preliminary findings.