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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Roles of Education and IQ in Cognitive Reserve in Parkinson's Disease-Mild Cognitive Impairment
M J Armstrong1, G Naglie, S Duff-Canning
1Toronto Western Hospital Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Ont., Canada.
Background/Aims:
The role of cognitive reserve in Parkinson's disease (PD)-mild cognitive impairment (MCI) is incompletely understood.
Methods:
The relationships between PD-MCI, years of education, and estimated premorbid IQ were examined in 119 consecutive non-demented PD patients using logistic regression models.
Results:
Higher education and IQ were associated with reduced odds of PD-MCI in univariate analysis. In multivariable analysis, a higher IQ was associated with a significantly decreased odds of PD-MCI, but education was not.
Conclusion:
The association of higher IQ and decreased odds of PD-MCI supports a role for cognitive reserve in PD, but further studies are needed to clarify the interaction of IQ and education and the impact of other contributors such as employment and hobbies.
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