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Uterine leiomyomas in pregnancy: a prospective study
J L Davis1, S Ray-Mazumder, C J Hobel
1Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California.
Obstetrics and Gynecology
|January 1, 1990
Summary
Uterine fibroids (leiomyomas) during pregnancy did not affect pregnancy outcomes based on size, number, or location. However, women with fibroids delivered earlier, indicated by a lower mean gestational age.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Medicine
Background:
- Uterine leiomyomas, commonly known as fibroids, are frequent benign tumors in women of reproductive age.
- Fibroids can present complications during pregnancy, necessitating careful monitoring and evaluation.
Purpose of the Study:
- To investigate the impact of uterine leiomyoma characteristics (size, number, location) on pregnancy outcomes.
- To compare pregnancy outcomes between women with and without uterine leiomyomas.
Main Methods:
- Prospective study involving 85 pregnant women with diagnosed uterine leiomyomas via ultrasound.
- Matching of leiomyoma patients with controls based on age, race, and parity.
- Follow-up throughout pregnancy to compare outcomes between groups.
Main Results:
- The size, number, or location of uterine leiomyomas did not significantly influence pregnancy outcomes.
- Women with uterine leiomyomas had a significantly lower mean gestational age at delivery compared to controls (P < .01).
Conclusions:
- Uterine leiomyoma characteristics do not appear to be a determining factor for adverse pregnancy outcomes.
- Pregnancy in the presence of uterine leiomyomas is associated with a tendency towards earlier delivery.