Uterine leiomyomas in pregnancy: a prospective study

Uterine leiomyomas are associated with various complications during pregnancy. During a 2-year period, pregnant women with a history of leiomyomas were referred to our antenatal testing unit for ultrasound evaluation. Eighty-five patients were found to have single or multiple leiomyomas by ultrasound examination. The size (total leiomyoma volume), number, and location of the leiomyoma(s) were ascertained. Each woman with leiomyoma(s) was matched by age, race, and parity with one without leiomyomas. Both groups were followed throughout pregnancy, and outcomes were compared. Size, number, or location of the leiomyoma had no influence on outcome. Student t test indicated a significantly (P less than .01) lower mean gestational age at the time of delivery in women with leiomyomas.