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Updated: May 18, 2026

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
Published on: December 23, 2022
Complete genome sequence of the porcine isolate Enterococcus faecalis D32
Melanie Zischka1, Carsten Kuenne, Jochen Blom
1Department of Infectious Diseases, Robert Koch Institute, Wernigerode Branch, Wernigerode, Germany.
The genome of Enterococcus faecalis D32, a pig-associated bacterium, was sequenced. This analysis revealed adaptations to its host but no clear signs of virulence factors.
Area of Science:
- Microbiology
- Genomics
- Veterinary Science
Background:
- Enterococcus faecalis is a common bacterium found in various environments, including animal hosts.
- Understanding the genetic makeup of commensal strains is crucial for assessing their potential impact on host health.
Purpose of the Study:
- To provide a complete and annotated genome sequence of Enterococcus faecalis D32.
- To investigate potential adaptations of this strain to its porcine host.
- To identify the presence or absence of distinct virulence-associated traits.
Main Methods:
- Whole-genome sequencing of Enterococcus faecalis D32.
- Bioinformatic analysis for genome annotation.
- Comparative genomics to identify host-specific adaptations and virulence factors.
Main Results:
- The genome sequence of Enterococcus faecalis D32 has been successfully obtained and annotated.
- Putative genetic adaptations suggesting specialization for the Danish pig host were identified.
- No distinct virulence-associated genes or traits were found in this commensal strain.
Conclusions:
- The genome sequence of Enterococcus faecalis D32 offers valuable insights into the adaptation of commensal bacteria to porcine hosts.
- The absence of significant virulence factors suggests a low pathogenic potential for this strain in its natural environment.
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