Related Experiment Video
Updated: May 18, 2026

Rapid In Situ Hybridization using Oligonucleotide Probes on Paraformaldehyde-prefixed Brain of Rats with Serotonin Syndrome
Published on: September 23, 2015
The microwave spectrum of neurotransmitter serotonin
Carlos Cabezas1, Marcelino Varela, Isabel Peña
1Grupo de Espectroscopía Molecular (GEM), Edificio Quifima, Laboratorios de Espectroscopia y Bioespectroscopia, Parque Científico UVa, Universidad de Valladolid, 47005 Valladolid, Spain.
Abstract:
A laser ablation device in combination with a molecular beam Fourier-transform microwave spectrometer has allowed the observation of the rotational spectrum of serotonin for the first time. Three conformers of the neurotransmitter have been detected and characterized in the 4-10 GHz frequency range. The complicated hyperfine structure arising from the presence of two (14)N nuclei has been fully resolved for all conformers and used for their identification. Nuclear quadrupole coupling constants of the nitrogen atom of the side chain have been used to determine the orientation of the amino group probing the existence of N-Hπ interactions involving the amino group and the pyrrole unit in the Gauche-Phenyl conformer (GPh) or the phenyl unit in the Gauche-Pyrrole (GPy) ones.
More Related Videos
11:27The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System
Published on: April 25, 2012
13:56The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism
Published on: November 19, 2014
Related Concept Videos
The Electromagnetic Spectrum
The Electromagnetic Spectrum
Standing Waves in a Cavity
IR Spectrum
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0% (complete...
Molecular Spectroscopy: Absorption and Emission
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences