Urethral reconstruction in lichen sclerosus
Enzo Palminteri1, Steven B Brandes, Miroslav Djordjevic
1Center for Urethral and Genitalia Reconstructive Surgery, Arezzo, Italy. enzo.palminteri@inwind.it
Current Opinion in Urology
|September 12, 2012
Summary
Surgical management of urethral strictures from lichen sclerosus (LS) primarily involves oral mucosa grafts. Perineal urethrostomy serves as a salvage option for severe cases, with long-term follow-up crucial for managing this chronic condition.
Area of Science:
- Urology
- Dermatology
- Surgical Oncology
Background:
- Lichen sclerosus (LS) is a chronic inflammatory skin condition.
- LS commonly affects the anogenital region.
- Anogenital LS can lead to urethral stenosis, posing surgical challenges.
Purpose of the Study:
- To review surgical management options for urethral strictures caused by LS.
- To evaluate the efficacy of different reconstructive techniques.
- To provide guidance on managing LS-induced urethral strictures.
Main Methods:
- Review of surgical techniques for LS urethral strictures.
- Analysis of graft materials and reconstructive approaches.
- Evaluation of outcomes and salvage procedures.
Main Results:
- Oral mucosa grafts are recommended for one-stage or staged repairs.
- Skin grafts/flaps are contraindicated due to potential LS involvement.
- Perineal urethrostomy is a salvage option for severe panurethral strictures.
Conclusions:
- Oral mucosa grafts are the preferred treatment for LS urethral strictures.
- Perineal urethrostomy is vital in complex, severe cases.
- Long-term patient follow-up and counseling are essential for managing LS progression.


