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Published on: May 22, 2020

Prolonged fever after Infliximab infusion

Jennifer Katz1, Michael Frank

  • 1Jennifer Katz, Michael Frank, New York University Medical Center, New York, NY 10016, United States.

World Journal of Gastrointestinal Pharmacology and Therapeutics
|September 12, 2012
PubMed

Pharmacologic management for ulcerative colitis (UC) has recently been expanded to include anti- tumor necrosis factor (TNF) therapy for severe disease. Infliximab, a chimeric monoclonal antibody directed again TNF α was first tested in patients with Crohn's disease. In addition to serious infections, malignancy, drug induced lupus and other autoimmune diseases, serum sickness-like reactions, neurological disease, and infusion reactions further complicate the use of Infliximab. We report a case of prolonged fever after Infliximab infusion to treat steroid refractory UC.

Keywords:
Crohn’s diseaseFeverInfliximabUlcerative colitis

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