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Updated: May 18, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Tissue layer image of the photoreceptor layer in central serous chorioretinopathy using SD-OCT
Ik Soo Byon1, Hyun Jun Park, Sung Who Park
1Department of Ophthalmology, Pusan National University Hospital, Busan Korea.
Background And Objective:
To investigate the findings of a tissue layer image of the photoreceptor layer, or photoreceptor layer map (PLM), using spectral-domain optical coherence tomography (SD-OCT) in central serous chorioretinopathy (CSC).
Patients And Methods:
Data scanned using SD-OCT in CSC were processed to obtain PLMs, which were analyzed and compared with fluorescein angiography and OCT.
Results:
Among 72 eyes of 69 patients, PLMs depicted subretinal fluid as distinct hyporeflective areas in 71 eyes (98.6% sensitivity). Attenuated signals at the junction of the inner and outer segments of the photoreceptors in OCT were depicted as relative hyporeflective areas corresponding to the areas of previous subretinal fluid and its recent reduction. After resolution of subretinal fluid, foveal reflectivity was correlated with visual acuity (P = .040; r = 0.41).
Conclusion:
PLM is a useful adjuvant image for managing CSC because it shows the photoreceptor layer and subretinal fluid as a fundus image.

