Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A summary guide for detecting and reducing nitrous oxide infrastructure leaks in healthcare facilities.

Anaesthesia and intensive care·2026
Same author

Rare but High-consequence Cardiac Events During Thoracic Endovascular Aortic Repair: Implications for Intraoperative Vigilance.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Erratum: Design and Staged Implementation of a Multidisciplinary Preoperative Anemia Clinic at a Tertiary Care Medical Center.

Anesthesia and analgesia·2026
Same author

Tracheal agenesis diagnosed by supraglottic airway-assisted endoscopic evaluation during neonatal resuscitation: a case report.

JA clinical reports·2026
Same author

Primary anesthesia provider characteristics and risk factors for intraoperative medication errors: a retrospective cohort study.

BMC anesthesiology·2025
Same author

Anesthesia and Babies' Brains: Lessons from the Lounge.

Anesthesiology·2025
Same journal

Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports.

Paediatric anaesthesia·2026
Same journal

Inflammatory Indices and Pediatric Emergence Delirium: Predictive Signal or Statistical Artifact?

Paediatric anaesthesia·2026
Same journal

Perspectives in Pediatric Ambulatory Anesthesia: Part 1-One Center's 15 Year Evolution in Eligibility, Utilization, Efficiency, and Outcomes.

Paediatric anaesthesia·2026
Same journal

Retrospective Evaluation of an Artificial Intelligence-Assisted Video Laryngoscope System for Tracheal Intubation in Infants and Neonates.

Paediatric anaesthesia·2026
Same journal

Perspectives in Pediatric Ambulatory Anesthesia: Part 2-One Center's 15 Year Experience Improving Quality and Safety Outcomes.

Paediatric anaesthesia·2026
Same journal

Response to: Reliability of the Pediatric Specific ASA Physical Status Classification.

Paediatric anaesthesia·2026
See all related articles

Related Experiment Video

Updated: May 18, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

New technologies in pediatric anesthesia.

Helen Holtby1, Justin J Skowno, Daryl J Kor

  • 1Hospital of Sick Children, Toronto, ON, Canada.

Paediatric Anaesthesia
|September 13, 2012
PubMed
Summary
This summary is machine-generated.

This review explores three innovative technologies for pediatric care: non-invasive hemoglobin monitoring, continuous cardiac output monitoring, and anesthesia information management systems, aiming to improve patient outcomes.

Related Experiment Videos

Last Updated: May 18, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

Area of Science:

  • Pediatric Anesthesiology
  • Medical Technology Innovation
  • Critical Care Monitoring

Background:

  • Current pediatric care faces challenges in continuous monitoring and data management.
  • Advancements in adult medicine offer potential for pediatric applications.
  • Non-invasive technologies are crucial for minimizing patient discomfort and risk.

Purpose of the Study:

  • To review emerging technologies with potential pediatric applications.
  • To highlight the benefits of pulse oximetry-based hemoglobin determination.
  • To discuss the utility of continuous cardiac output monitoring and anesthesia information management systems in pediatric settings.

Main Methods:

  • Review of current literature on three key technologies.
  • Analysis of potential applications in pediatric surgery and critical care.
  • Evaluation of technological capabilities for non-invasive and continuous monitoring.

Main Results:

  • Pulse oximetry-based hemoglobin determination may reduce venipuncture and transfusions in high-risk children.
  • Continuous cardiac output monitoring offers non-invasive hemodynamic assessment in pediatric patients.
  • Anesthesia information management systems can enhance clinical decisions and research.

Conclusions:

  • These technologies hold promise for improving pediatric patient safety and care.
  • Further research and integration are needed to fully realize their potential in pediatrics.
  • Non-invasive monitoring and data management are key areas for future development in pediatric medicine.