Supported oligomethionine sulfoxide and Ellman's reagent for cysteine bridges formation

Luisa Ronga1, Pascal Verdié, Pierre Sanchez

  • 1Genepep SA, Les Coteaux Saint Roch, 12 Rue du Fer à Cheval, 34430 St Jean de Védas, France.

Amino Acids
|September 13, 2012
PubMed

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Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.