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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic cells are...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

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Mesenchymal stromal cells in the regeneration of radiation-induced organ sequelae: will they make the difference?

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Related Experiment Video

Updated: May 18, 2026

Human Mesenchymal Stem Cell Processing for Clinical Applications Using a Closed Semi-Automated Workflow
09:03

Human Mesenchymal Stem Cell Processing for Clinical Applications Using a Closed Semi-Automated Workflow

Published on: March 17, 2023

Stem cell therapy: from bench to bedside.

R Tamarat1, J J Lataillade, E Bey

  • 1Institute of Radioprotection and Nuclear Safety (IRSN), DRPH/SRBE/LRTE, BP 17, Fontenay-aux-Roses Cedex 92262, France. radia.tamarat@irsn.fr

Radiation Protection Dosimetry
|September 13, 2012
PubMed
Summary
This summary is machine-generated.

Adult mesenchymal stem cell therapy shows promise for treating radiation skin injuries, aiding wound repair and potentially preventing amputation. Further research is needed to optimize its use in managing radiological burns.

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An Enzymatic Method to Rescue Mesenchymal Stem Cells from Clotted Bone Marrow Samples

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Last Updated: May 18, 2026

Human Mesenchymal Stem Cell Processing for Clinical Applications Using a Closed Semi-Automated Workflow
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Human Mesenchymal Stem Cell Processing for Clinical Applications Using a Closed Semi-Automated Workflow

Published on: March 17, 2023

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies
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Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Published on: July 19, 2007

An Enzymatic Method to Rescue Mesenchymal Stem Cells from Clotted Bone Marrow Samples
08:58

An Enzymatic Method to Rescue Mesenchymal Stem Cells from Clotted Bone Marrow Samples

Published on: April 12, 2015

Area of Science:

  • Regenerative Medicine
  • Dermatology
  • Radiation Oncology

Background:

  • Radiation toxicity poses risks in cancer treatment and bioterrorism.
  • Radiation injuries, including skin damage and impaired wound healing, are linked to angiogenesis deficiency and vascular damage.
  • Current treatments for severe radiation lesions often lead to amputation.

Purpose of the Study:

  • To review advances in stem cell therapy for managing radiation-induced skin injuries.
  • To explore strategies for enhancing stem cell therapy efficacy in irradiated tissues.

Main Methods:

  • Review of current and evolving basic and translational research.
  • Analysis of adult mesenchymal stem cell therapy applications in radiation injury.

Main Results:

  • Adult mesenchymal stem cell therapy has been successfully applied in patients with accidental radiation injuries, sometimes combined with surgery.
  • Significant progress has been made in radiation skin injury management over the last decade.

Conclusions:

  • Stem cell therapy is a promising approach for treating radiation skin injuries.
  • Further strategies are required to maximize the benefits of stem cell therapy and overcome the challenges of the irradiated tissue environment.