Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aspiration and Bronchoscopic Retrieval of Dental Objects: A Literature Review and Data Analysis of Reported Cases.

Journal of bronchology & interventional pulmonology·2026
Same author

Positive fluid balance is associated with earlier acute kidney injury in COVID-19 patients.

Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)·2026
Same author

Development of a Pelvic Organ Prolapse Misconceptions Scale for Hispanic Women.

International urogynecology journal·2026
Same author

Operator radiation exposure comparing left-radial artery and right-radial artery approaches: A systematic review and meta-analysis.

American heart journal·2026
Same author

Improving internal medicine resident proficiency in non-invasive positive pressure ventilation and oxygen modalities through simulation training.

Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR·2026
Same author

Evaluating the impact of social media reminders on outpatient appointment attendance among diabetes patients using continuous glucose monitors: a retrospective study.

Proceedings (Baylor University. Medical Center)·2026

Related Experiment Video

Updated: May 18, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Chronic methadone use, poor bowel visualization and failed colonoscopy: a preliminary study.

Siddharth Verma1, Joshua Fogel, David J Beyda

  • 1Department of Internal Medicine, Division of Gastroenterology, New York Methodist Hospital, Weill Cornell Medical College, Brooklyn, NY 11215, United States. vermasi@hotmail.com

World Journal of Gastroenterology
|September 13, 2012
PubMed
Summary

Chronic methadone use significantly impairs colonoscopy visualization and preparation, increasing the need for repeat procedures. Patients on methadone may require more aggressive bowel preparation for effective colonoscopy.

Keywords:
ColonoscopyColonoscopy preparationInadequate bowel preparationMethadoneMethadone doseOpioid

More Related Videos

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Related Experiment Videos

Last Updated: May 18, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

Area of Science:

  • Gastroenterology
  • Clinical Pharmacology
  • Endoscopy

Background:

  • Chronic methadone dependence is prevalent in various patient populations.
  • Opioid agonists like methadone can affect gastrointestinal motility.
  • Effective colonoscopy relies on adequate bowel visualization and preparation.

Purpose of the Study:

  • To investigate the impact of chronic methadone usage on the quality of colonoscopy.
  • To assess differences in bowel visualization and preparation between methadone-dependent patients and controls.
  • To determine if methadone use influences the requirement for repeat colonoscopies.

Main Methods:

  • Retrospective analysis of colonoscopy reports from methadone-dependent (MD) patients and opioid-naive controls (C).
  • Exclusion of patients with known risk factors for constipation or dysmotility.
  • Evaluation of bowel visualization (4-point scale), preparation quality (good, fair, poor), and need for repeat colonoscopy.
  • Statistical analysis using ANOVA and Pearson chi-squared test, including univariate and multivariate logistic regression.

Main Results:

  • MD patients exhibited significantly poorer bowel visualization (40.3% solid stool) compared to controls (6.9%, P < 0.001).
  • Poor bowel preparation (35.8% vs 9.7%, P < 0.001) and higher rates of repeat colonoscopy (32.8% vs 12.5%, P = 0.004) were observed in MD patients.
  • Solid stool was independently associated with methadone dependence (OR, 7.77; P = 0.01), and higher methadone doses correlated with poorer visualization.

Conclusions:

  • Methadone dependence is a significant risk factor for suboptimal bowel visualization during colonoscopy.
  • Methadone-dependent patients are more likely to require repeat colonoscopies due to inadequate preparation.
  • Consideration of more aggressive bowel preparation protocols is recommended for methadone-dependent patients undergoing colonoscopy.