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Updated: May 18, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
2,2'-{[2-(Pyridin-2-yl)-1,3-diazinane-1,3-diyl]bis(methylene)}diphenol
Adailton J Bortoluzzi1, Geovana G Terra
1Depto. de Química, Universidade Federal de Santa Catarina, 88040-900 - Florianópolis, SC, Brazil.
Abstract:
The title compound, C(23)H(25)N(3)O(2), was obtained as an inter-mediary in the preparation of non-symmetric tertiary diamines. The mol-ecular structure presents T-shaped spatial form, in which the pyrimidine ring exhibits a chair conformation. The pyridyl ring is almost perpendicular to the phenyl rings with dihedral angles of 80.17 (8) and 76.03 (2)°. The phenol and amine groups are involved in two strong intra-molecular O-H⋯N inter-actions. In the crystal, the mol-ecules are stacked along [010]; however, no inter-molecular inter-actions are observed.
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