N-[(2S)-2-Chloro-propano-yl]glycine
Acta Crystallographica. Section E, Structure Reports Online
|September 13, 2012
Summary
Researchers synthesized a novel compound, C(5)H(8)ClNO(3), using a nucleophilic substitution reaction. Crystal analysis revealed specific molecular arrangements and hydrogen bonding, forming a stable three-dimensional network.
Area of Science:
- Organic Chemistry
- Crystallography
Background:
- The synthesis of novel organic compounds is crucial for developing new materials and pharmaceuticals.
- Understanding crystal packing and intermolecular interactions aids in predicting material properties.
Purpose of the Study:
- To synthesize and characterize a new compound with the chemical formula C(5)H(8)ClNO(3).
- To investigate the molecular structure and crystal packing of the synthesized compound.
Main Methods:
- Nucleophilic substitution reaction between (2S)-2-chloro-propanoyl chloride and glycine.
- X-ray crystallography to determine the molecular structure and hydrogen bonding patterns.
Main Results:
- Successful synthesis of the title compound C(5)H(8)ClNO(3).
- The acetate group exhibited a dihedral angle of 84.6° with the C-NH-C=O plane.
- Formation of a three-dimensional crystal network via N-H⋯O and O-H⋯O hydrogen bonds.
Conclusions:
- The study reports the successful synthesis and structural elucidation of a new organic compound.
- The observed hydrogen bonding network effectively stabilizes the crystal structure.
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