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Related Concept Videos

Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...

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Imported submicroscopic malaria in Madrid.

Germán Ramírez-Olivencia1, José Miguel Rubio, Pablo Rivas

  • 1Unit of Tropical Medicine, Infectious Disease Department, Hospital Carlos III, 1028029, Madrid, Spain. germanro.76@gmail.com

Malaria Journal
|September 14, 2012
PubMed
Summary
This summary is machine-generated.

Submicroscopic malaria (SMM) is common in imported cases, often asymptomatic but detectable by PCR. This highlights the need for vigilance in tropical medicine units to prevent potential transmission.

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Area of Science:

  • Tropical Medicine
  • Infectious Diseases
  • Parasitology

Background:

  • Submicroscopic malaria (SMM) involves low-density Plasmodium infections missed by microscopy.
  • SMM contributes to malaria transmission despite infrequent acute symptoms.
  • Imported SMM remains poorly characterized.

Purpose of the Study:

  • Determine the frequency of imported SMM.
  • Describe epidemiological, laboratory, and clinical features of imported SMM.

Main Methods:

  • Retrospective review of medical records (2002-2007) at a Tropical Medicine Unit.
  • Standard microscopy (Field stain, thick/thin smears) for Plasmodium detection.
  • Semi-nested multiplex malaria PCR for low-parasitemia diagnosis.

Main Results:

  • SMM accounted for 35.5% of malaria cases (104 patients).
  • Most cases were immigrants from Equatorial Guinea; 28.8% were symptomatic.
  • Common symptoms included asthenia, fever, and arthralgias; lab findings showed anemia, leukopenia, and thrombocytopenia.

Conclusions:

  • Imported SMM is a significant entity in tropical medicine settings.
  • Asymptomatic SMM can present with fever or laboratory abnormalities.
  • Consideration of SMM is crucial for preventing potential malaria re-emergence, especially with vector presence in Europe.