Multiregional embolizations and Takotsubo cardiomyopathy associated with left atrial myxoma

Suk Min Seo1, Sung Kyun Park, Sung Jun Kim

  • 1Cardiovascular Center and Cardiology Division, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.

Insights

Cardiac myxoma, a common benign heart tumor, can cause widespread embolisms. This report details rare cases of tumor spread beyond the brain in patients with left atrial myxoma.

Area of Science:

  • Cardiology
  • Oncology
  • Neurology

Background:

  • Cardiac myxoma is the most frequent primary cardiac neoplasm, comprising approximately 75% of benign cardiac tumors.
  • Tumor embolization is a known complication, affecting 30% to 40% of myxoma patients, with cerebral artery involvement being most common.

Observation:

  • This report presents a rare case of multiregional tumor embolizations.
  • The embolizations occurred in locations other than the cerebral arteries.
  • Takotsubo cardiomyopathy was also observed in a patient with left atrial myxoma.

Findings:

  • This study documents the first reported instance of multiregional tumor embolizations, excluding cerebral arteries, in patients with left atrial myxoma.
  • The findings highlight the potential for widespread metastatic spread from cardiac myxoma.

Implications:

  • These findings expand the understanding of cardiac myxoma's embolic potential.
  • Clinicians should consider broader diagnostic workups for patients with left atrial myxoma presenting with embolic phenomena.
  • Further research is warranted to elucidate the mechanisms and clinical significance of non-cerebral embolizations from cardiac myxoma.

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