Multiregional embolizations and Takotsubo cardiomyopathy associated with left atrial myxoma
Suk Min Seo1, Sung Kyun Park, Sung Jun Kim
1Cardiovascular Center and Cardiology Division, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.
Insights
Cardiac myxoma, a common benign heart tumor, can cause widespread embolisms. This report details rare cases of tumor spread beyond the brain in patients with left atrial myxoma.
Area of Science:
- Cardiology
- Oncology
- Neurology
Background:
- Cardiac myxoma is the most frequent primary cardiac neoplasm, comprising approximately 75% of benign cardiac tumors.
- Tumor embolization is a known complication, affecting 30% to 40% of myxoma patients, with cerebral artery involvement being most common.
Observation:
- This report presents a rare case of multiregional tumor embolizations.
- The embolizations occurred in locations other than the cerebral arteries.
- Takotsubo cardiomyopathy was also observed in a patient with left atrial myxoma.
Findings:
- This study documents the first reported instance of multiregional tumor embolizations, excluding cerebral arteries, in patients with left atrial myxoma.
- The findings highlight the potential for widespread metastatic spread from cardiac myxoma.
Implications:
- These findings expand the understanding of cardiac myxoma's embolic potential.
- Clinicians should consider broader diagnostic workups for patients with left atrial myxoma presenting with embolic phenomena.
- Further research is warranted to elucidate the mechanisms and clinical significance of non-cerebral embolizations from cardiac myxoma.
Abstract:
Cardiac myxoma represents the most common primary cardiac neoplasm, accounting for nearly 75% of benign cardiac tumor. Tumor embolisms occur in 30% to 40% of patients with myxoma, and half of these are cerebral arteries. To our knowledge, this is the first published report of multiregional tumor embolizations except for cerebral artery and Takotsubo cardiomyopathy in patients with left atrial myxoma.
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