Related Experiment Video
Updated: May 18, 2026

Monitoring Blood Glucose in Mouse Offspring After Intracytoplasmic Sperm Injection
Published on: May 17, 2024
Maternal glucose administration for facilitating tests of fetal wellbeing
Kelvin H Tan1, Antoinette Sabapathy
1Department of Maternal Fetal Medicine, KK Women’s and Children’s Hospital, Singapore, Singapore. khtan@tan.net.
Background:
Antenatal maternal glucose administration has been suggested to improve the efficiency of antepartum fetal heart rate testing.
Objectives:
The objective of this review was to assess the merits or adverse effects of antenatal maternal glucose administration in conjunction with tests of fetal wellbeing.
Search Methods:
We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (6 July 2012).
Selection Criteria:
All published and unpublished randomized controlled trials assessing the merits of antenatal maternal (oral or intravenous) glucose administration in conjunction with tests of fetal wellbeing.
Data Collection And Analysis:
Both review authors independently extracted data and assessed trial quality. Authors of published and unpublished trials were contacted for further information.
Main Results:
A total of two trials, involving 708 participants, were included. Antenatal maternal glucose administration did not decrease the incidence of non-reactive antenatal cardiotocography tests.
Authors' Conclusions:
Antenatal maternal glucose administration has not been shown to reduce non-reactive cardiotocography. More trials are needed to further substantiate this and to determine not only the optimum dose, but also to evaluate the efficacy, predictive reliability, safety and perinatal outcome of glucose administration in conjunction with cardiotocography and also other tests of fetal wellbeing.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Hyperglycemia
Hypoglycemia and Glucagon
Glucose Transporters
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
