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Updated: Apr 28, 2026

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
Published on: February 15, 2019
Diversity, stability and resilience of the human gut microbiota
Catherine A Lozupone1, Jesse I Stombaugh, Jeffrey I Gordon
1Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, USA.
Abstract:
Trillions of microbes inhabit the human intestine, forming a complex ecological community that influences normal physiology and susceptibility to disease through its collective metabolic activities and host interactions. Understanding the factors that underlie changes in the composition and function of the gut microbiota will aid in the design of therapies that target it. This goal is formidable. The gut microbiota is immensely diverse, varies between individuals and can fluctuate over time - especially during disease and early development. Viewing the microbiota from an ecological perspective could provide insight into how to promote health by targeting this microbial community in clinical treatments.
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