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Compact Quantum Dots for Single-molecule Imaging
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Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

NIR fluorescent biotinylated cyanine dye: optical properties and combination with quantum dots as a potential sensing

Guillermo O Menéndez1, María Eva Pichel, Carla C Spagnuolo

  • 1Dpto. de Química Orgánica, CIHIDECAR-CONICET, Fac. Cs. Exactas y Nat., Universidad de Buenos Aires Int., Güiraldes 2160, Pabellón II, Cdad. Universitaria (1428), Cdad. Autónoma de Buenos Aires, Argentina.

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology
|September 14, 2012
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...