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Related Concept Videos

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Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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Drugs such as carbonic anhydrase inhibitors, α2- and...
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Glaucoma: Overview

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Angle Closure Glaucoma: Treatment

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Related Experiment Video

Updated: May 18, 2026

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography
05:14

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography

Published on: August 11, 2023

[Inflammatory choroidal neovascularisations].

S Winterhalter1, A M Joussen, U Pleyer

  • 1Klinik für Augenheilkunde, Charité Universitätsmedizin Berlin. Sibylle.Winterhalter@charite.de

Klinische Monatsblatter Fur Augenheilkunde
|September 14, 2012
PubMed
Summary
This summary is machine-generated.

Inflammation-induced choroidal neovascular membranes (CNV) from posterior uveitis are treatable. Controlling intraocular inflammation is crucial for managing these inflammatory CNV.

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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
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Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography
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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
09:56

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

Published on: January 21, 2018

Area of Science:

  • Ophthalmology
  • Immunology
  • Vascular Biology

Context:

  • Posterior uveitis, including presumed ocular histoplasmosis syndrome (POHS), multifocal choroiditis (MFC), and punctate inner choroidopathy (PIC), frequently leads to choroidal neovascular membranes (CNV).
  • Inflammatory processes are a primary driver for the development of these neovascular membranes, often presenting as classical forms.

Purpose:

  • To explore the link between inflammatory conditions and the development of choroidal neovascular membranes (CNV).
  • To discuss the treatment outcomes for inflammatory CNV compared to age-related macular degeneration (AMD) CNV.
  • To emphasize the importance of managing intraocular inflammation in CNV treatment.

Summary:

  • Inflammatory CNV, often associated with posterior uveitis, typically presents as classical membranes.
  • These inflammatory membranes are often smaller and occur in younger patients, leading to better treatment outcomes compared to AMD-related CNV.
  • Treatment has evolved from laser coagulation and photodynamic therapy (PDT) to anti-VEGF injections, often combined with PDT, yielding improved visual acuity.

Impact:

  • Effective management of inflammatory CNV is achievable with current therapies, including anti-VEGF agents.
  • Controlling underlying intraocular inflammation is paramount, as it is the primary trigger for CNV formation.
  • Understanding the inflammatory etiology of CNV aids in developing targeted treatment strategies and improving patient prognosis.