Related Experiment Video
Updated: May 18, 2026

07:59
Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
Published on: April 25, 2025
Rapid detection of carbapenemase-producing Pseudomonas spp
Laurent Dortet1, Laurent Poirel, Patrice Nordmann
1Service de Bactériologie-Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, K.-Bicêtre, France.
Journal of Clinical Microbiology
|September 14, 2012
Summary
The Carba NP test accurately detects carbapenemase production in Pseudomonas species. This rapid, cost-effective method is a reliable tool for microbiology labs.
Area of Science:
- Clinical microbiology
- Biochemical diagnostics
Background:
- Carbapenemase-producing bacteria pose a significant public health threat.
- Rapid and accurate detection of carbapenemase production is crucial for infection control.
Purpose of the Study:
- To evaluate the Carba NP test for detecting carbapenemase production in Pseudomonas species.
Main Methods:
- The Carba NP test was employed to identify carbapenemase production.
- Performance metrics including specificity and sensitivity were assessed.
Main Results:
- The Carba NP test demonstrated high specificity (100%) and sensitivity (94.4%).
- The test provided results in under 2 hours, indicating its rapid nature.
Conclusions:
- The Carba NP test is a reliable, rapid, and cost-effective method for identifying carbapenemase-producing Pseudomonas species.
- This technique is suitable for implementation in standard microbiology laboratories.
