Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pectoralis major muscle defect and Poland complex.

E E Castilla, J E Paz, I M Orioli

    American Journal of Medical Genetics
    |January 1, 1979
    PubMed
    Summary

    Pectoralis major muscle defect (PMD) affects 1 in 22,189 infants, often unilaterally and more in males. Associated hand anomalies like syndactyly and congenital defects are noted, with potential links to first-trimester hormone exposure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Latin American Collaborative Study of Congenital Malformations (ECLAMC): a model for health collaborative studies.

    Public health genomics·2014
    Same author

    Hormone therapy during pregnancy and isolated hypospadias: an international case-control study.

    The International journal of risk & safety in medicine·2013
    Same author

    Birth defects monitoring in underdeveloped countries: an example from Uruguay.

    The International journal of risk & safety in medicine·2013
    Same author

    Fine-mapping of 5q12.1-13.3 unveils new genetic contributors to caries.

    Caries research·2013
    Same author

    Polymorphisms in the fetal progesterone receptor and a calcium-activated potassium channel isoform are associated with preterm birth in an Argentinian population.

    Journal of perinatology : official journal of the California Perinatal Association·2012
    Same author

    Association of AXIN2 with non-syndromic oral clefts in multiple populations.

    Journal of dental research·2012

    Area of Science:

    • Pediatrics
    • Medical Genetics
    • Congenital Anomalies

    Background:

    • Pectoralis major muscle defect (PMD) is a rare congenital condition.
    • Understanding its prevalence and associated anomalies is crucial for diagnosis and management.

    Purpose of the Study:

    • To determine the incidence of PMD in South American infants.
    • To investigate the clinical characteristics, associated anomalies, and potential risk factors for PMD.

    Main Methods:

    • Retrospective analysis of 599,109 live births in South America.
    • Detailed examination of 27 diagnosed cases of PMD for laterality, sex distribution, and associated conditions.

    Main Results:

    • PMD incidence was 1 in 22,189 live births.
    • Unilateral defects, predominantly right-sided (20/27) and male (19/27), were observed.
    • 12 cases had ipsilateral hand anomalies (hypoplasia/syndactyly), and 4 had other congenital anomalies. A correlation with first-trimester sex hormone intake and vaginal bleeding was noted.

    Conclusions:

    • PMD is a rare condition with specific epidemiological patterns.
    • Associated hand anomalies and other congenital defects frequently occur with PMD.
    • Potential links to maternal factors in early pregnancy warrant further investigation.

    Related Experiment Videos