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Updated: May 18, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
Published on: May 10, 2016
The future of human health risk assessment of environmental chemicals
1Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina, USA.
Abstract:
Dramatic changes are beginning to take place in risk assessment, changes that will involve rapid, high-throughput assays capable of analyzing large numbers of samples in a short time. These new systems will incorporate many of the aspects of cellular and molecular biology, including human and human-derived cell lines, toxicogenomics, proteomics, and metabolomics. The large amount of data generated will require a systems biology approach if it is to be reduced to generalizations of value in risk management. The current chapter briefly describes the emerging systems and their component parts.
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