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Related Experiment Videos

Naevus corniculatus: a new acantholytic disorder.

R Happle1, P M Steijlen, G Kolde

  • 1Department of Dermatology, University of Nijmegen, The Netherlands.

The British Journal of Dermatology
|January 1, 1990
PubMed
Summary

This study introduces

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Area of Science:

  • Dermatology and Genetic Skin Disorders

Background:

  • Epidermal nevi are congenital skin hamartomas.
  • Blaschko's lines represent patterns of somatic mosaicism.

Observation:

  • A 33-year-old man presented with a rare epidermal nevus.
  • The nevus exhibited Blaschko-linear distribution.
  • Lesions included filiform hyperkerkeratoses, cutaneous horns, and comedone-like structures.

Findings:

  • Histopathology revealed acantholysis without dyskeratosis in all lesions.
  • The proposed term 'naevus corniculatus' reflects the horn-like features.
  • This condition presents a unique combination of epidermal abnormalities.

Implications:

  • This case expands the spectrum of epidermal nevi.
  • Understanding acantholysis in this context may offer new insights.
  • The term 'naevus corniculatus' aids in classifying this distinct dermatosis.

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