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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
Solid-in-oil dispersion: a novel core technology for drug delivery systems
Yoshiro Tahara1, Noriho Kamiya, Masahiro Goto
1Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Moto-oka, Fukuoka 819-0395, Japan.
International Journal of Pharmaceutics
|September 15, 2012
Summary
Solid-in-oil (S/O) dispersions, initially for enzymatic catalysis, are now advanced drug delivery systems. This review covers their preparation, features, and innovative oral and skin applications.
Area of Science:
- Pharmaceutical Sciences
- Materials Science
- Biotechnology
Background:
- Solid-in-oil (S/O) dispersions, a key technology, have seen significant advancement in drug delivery over the last decade.
- Originally developed in 1997 for enzymatic catalysis in organic media, these oil-based protein dispersions showed broad research potential.
Purpose of the Study:
- To present the history and characteristics of novel S/O dispersion preparation methods.
- To discuss recent research on S/O dispersions for innovative drug delivery systems.
Main Methods:
- Review of historical development of S/O dispersion preparation techniques.
- Analysis of recent studies on S/O dispersion applications in drug delivery.
Main Results:
- Established a novel, effective, and practical method for S/O dispersion preparation.
- Demonstrated the successful adaptation of S/O dispersions for drug delivery applications.
Conclusions:
- S/O dispersions offer a versatile platform for advanced drug delivery.
- Recent innovations focus on oral and skin drug delivery systems utilizing S/O technology.
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