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Updated: May 18, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Panhypopituitarism due to craniopharyngioma associated with hyperthyroidism caused by graves' disease
María Peralta Watt1, David Peñalver Talavera
1Unidad de Endocrinología y Nutrición. Hospital Virgen del Puerto. Plasencia. Cáceres. España.
Abstract:
Craniopharyngiomas are unusual tumors that are mainly located in the sella turcica or parasellar structures. These tumors can produce multiple neurological and visual symptoms or manifestations due to involvement of the hypothalamic-pituitary axis. Pituitary manifestations can be produced by involvement of the anterior or posterior pituitary and contribute to the substantial morbidity and mortality associated with these tumors, despite their benign histology. We present the case of a woman with a craniopharyngioma that produced panhypopituitarism and diabetes insipidus, in whom diagnosis was hampered by the development of primary hyperthyroidism due to Graves' disease during the diagnostic process.
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